Title : Transection of intrinsic polysynaptic pathways reduces N-methyl-D-aspartate neurotoxicity in hippocampal slice cultures.

Pub. Date : 2003 Jul

PMID : 12804798






2 Functional Relationships(s)
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1 NMDA exposure produced significant excitotoxicity in all regions (160-500% of control), particularly in the CA1. N-Methylaspartate carbonic anhydrase 1 Homo sapiens
2 Surgical transection of mossy fibers and Schaffer collaterals significantly reduced NMDA-induced neurotoxicity in the CA1 ( approximately 20%), and to a lesser extent, the CA3 and dentate regions. N-Methylaspartate carbonic anhydrase 1 Homo sapiens