Title : Expression of the hemochromatosis (HFE) gene modulates the cellular uptake of 67Ga.

Pub. Date : 2003 Jun

PMID : 12791823






2 Functional Relationships(s)
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1 CONCLUSION: Our studies suggest that expression of wild-type HFE in cells produces a decrease in (67)Ga uptake due to a reduction in available Tf binding sites for (67)Ga-Tf on the TfR. Gallium homeostatic iron regulator Homo sapiens
2 These results imply that (67)Ga uptake by cells with wild-type HFE may differ from cells with the HFE C282Y mutation. Gallium homeostatic iron regulator Homo sapiens