Title : The human kidney is a progesterone-metabolizing and androgen-producing organ.

Pub. Date : 2003 Jun

PMID : 12788891






2 Functional Relationships(s)
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1 The presence of 3 beta-HSD type 2 and P450c17 indicated that conversion of pregnenolone to dehydroepiandrosterone (DHEA) and to androstenedione may take place effectively in kidney. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 This resulted in efficient formation of DHEA from pregnenolone, indicating both 17 alpha-hydroxylase and 17,20-lyase activities exerted by P450c17. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens