Title : c-Fos is essential for the response of the tyrosine hydroxylase gene to depolarization or phorbol ester.

Pub. Date : 2003 Jun

PMID : 12787062






2 Functional Relationships(s)
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1 TH gene transcription rate increased from four- to eight-fold in control cells after treatment with either 50 mM KCl or TPA. Potassium Chloride tyrosine hydroxylase Rattus norvegicus
2 Stimulation of TH gene promoter activity, which was observed in control cell lines treated with either 50 mm KCl or TPA was also dramatically inhibited in the c-Fos-deficient cells. Potassium Chloride tyrosine hydroxylase Rattus norvegicus