Title : Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.

Pub. Date : 2003 Jun

PMID : 12756206






1 Functional Relationships(s)
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1 However, inhibition of the metabolism of (R)- and (S)-methadone by paroxetine was due to inhibition not only of CYP2D6, but also CYP3A4 and, to a minor extent, CYP2C8. Paroxetine cytochrome P450 family 3 subfamily A member 4 Homo sapiens