Title : Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells.

Pub. Date : 2003 Aug

PMID : 12754274






2 Functional Relationships(s)
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1 Adipose cells specialized in energy storage, contain large intracellular triglyceride-rich lipid droplets, are enriched with free cholesterol, and express sterol-regulated transcription factors such as liver X receptor (LXR). Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus
2 The recent identification of the LXR-dependent ATP binding cassette transporter A1 (ABCA1) pathway for cholesterol release from peripheral cells has led us to address the question of the expression and function of ABCA1 in adipocytes. Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus