Title : Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215.

Pub. Date : 2003 May 22

PMID : 12753909






1 Functional Relationships(s)
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1 This study establishes that HER2/HRG signaling selectively upregulates Tyr phosphorylation of c-Src at Tyr-215 located within the SH2 domain, increases c-Src kinase activity and selectively upregulates Tyr phosphorylation of FAK at Tyr-861. Tyrosine C-terminal Src kinase Homo sapiens