Pub. Date : 2003 May
PMID : 12737821
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin. | N-Acetylneuraminic Acid | sialic acid binding Ig like lectin 1 | Homo sapiens |
| 2 | The crystal structure of the N-terminal immunoglobulin-like domain of the Siglec sialoadhesin (SnD1) in complex with 2,3-sialyllactose has informed the design of sialic acid analogs (sialosides) that bind Siglecs with significantly enhanced affinities and specificities. | N-Acetylneuraminic Acid | sialic acid binding Ig like lectin 1 | Homo sapiens |