Title : Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal.

Pub. Date : 2003 Apr 15

PMID : 12716916






1 Functional Relationships(s)
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1 In this study, we show that orexin neurons, and not nearby LH neurons expressing melanin-concentrating hormone (MCH), have mu-opioid receptors and respond to chronic morphine administration and opiate antagonist-precipitated morphine withdrawal. Opiate Alkaloids hypocretin Mus musculus