Title : Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.

Pub. Date : 2003 Apr

PMID : 12711639






3 Functional Relationships(s)
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1 4 To investigate if nicotine could contribute to the increased CYP2E1 observed in alcoholic smokers, we treated human neuroblastoma IMR-32 cells in culture and found significantly higher CYP2E1 immunostaining in nicotine-treated cells (0.1-10 nM). Nicotine cytochrome P450 family 2 subfamily E member 1 Homo sapiens
2 4 To investigate if nicotine could contribute to the increased CYP2E1 observed in alcoholic smokers, we treated human neuroblastoma IMR-32 cells in culture and found significantly higher CYP2E1 immunostaining in nicotine-treated cells (0.1-10 nM). Nicotine cytochrome P450 family 2 subfamily E member 1 Homo sapiens
3 4 To investigate if nicotine could contribute to the increased CYP2E1 observed in alcoholic smokers, we treated human neuroblastoma IMR-32 cells in culture and found significantly higher CYP2E1 immunostaining in nicotine-treated cells (0.1-10 nM). Nicotine cytochrome P450 family 2 subfamily E member 1 Homo sapiens