Title : c-Fos-driven transcriptional activation of transforming growth factor beta-1: inhibition of high glucose-induced promoter activity by thiazolidinediones.

Pub. Date : 2003 May 2

PMID : 12711314






1 Functional Relationships(s)
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1 The TZD compounds troglitazone and rosiglitazone completely prevented the high glucose induction of both TGF-beta1 promoter activity and elevation in nuclear c-Fos protein levels. Rosiglitazone Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens