Title : Soybean isoflavones inhibit tumor necrosis factor-alpha-induced apoptosis and the production of interleukin-6 and prostaglandin E2 in osteoblastic cells.

Pub. Date : 2003 May

PMID : 12711143






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Soybean isoflavones inhibit tumor necrosis factor-alpha-induced apoptosis and the production of interleukin-6 and prostaglandin E2 in osteoblastic cells. Isoflavones interleukin 6 Mus musculus
2 Treatment with soybean isoflavones (10(-5)M), in the presence of TNF-alpha (10(-10)M), for 48 h inhibited production of IL-6 and PGE(2), suggesting the antiresorptive action of soy phytoestrogen may be mediated by decreases in these local factors. Isoflavones interleukin 6 Mus musculus