Title : Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro).

Pub. Date : 2003 Jan 25

PMID : 12706644






1 Functional Relationships(s)
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1 INTRODUCTION: The exchange of Aalpha 16, Arg for Cys or His is the most common molecular defect in dysfibrinogenemia directly affecting the thrombin cleavage site involved in fibrinopeptide A (FPA) release. Histidine coagulation factor II, thrombin Homo sapiens