Title : Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation.

Pub. Date : 2003 Jun 1

PMID : 12697837






3 Functional Relationships(s)
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Protein Name
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1 Phorbol esters such as 12-O-tetradeconylphorbol-13-acetate (TPA) activate protein kinase C, increase Connexin43 (Cx43) phosphorylation, and decrease cell-cell communication via gap junctions in many cell types. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens
2 Phorbol esters such as 12-O-tetradeconylphorbol-13-acetate (TPA) activate protein kinase C, increase Connexin43 (Cx43) phosphorylation, and decrease cell-cell communication via gap junctions in many cell types. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens
3 We show that this antibody detects Cx43 only when it is phosphorylated at S368 and, consistent with previous results, TPA treatment causes a dramatic increase in phosphorylation at S368. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens