Title : Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity.

Pub. Date : 2003 May

PMID : 12697832






2 Functional Relationships(s)
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1 Therefore, we addressed p300 control of basal and vitamin D(3)-enhanced activity of the OC promoter. Cholecalciferol bone gamma-carboxyglutamate protein Homo sapiens
2 We find that transient overexpression of p300 results in a significant dose-dependent increase of both basal and vitamin D(3)-stimulated OC gene activity. Cholecalciferol bone gamma-carboxyglutamate protein Homo sapiens