Title : Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia.

Pub. Date : 2003 Jun 1

PMID : 12689917






3 Functional Relationships(s)
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Protein Name
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1 In both populations, NOS3 genotype was significantly associated with tHcy concentrations in nonsmokers with low folate (P=0.03 for each). Folic Acid nitric oxide synthase 3 Homo sapiens
2 CONCLUSIONS: These data indicate that the NOS3 894TT genotype is a risk factor for elevated tHcy in healthy nonsmoking adults with low serum folate and supports the hypothesis that nitric oxide modulates homocysteine through an effect on folate catabolism. Folic Acid nitric oxide synthase 3 Homo sapiens
3 CONCLUSIONS: These data indicate that the NOS3 894TT genotype is a risk factor for elevated tHcy in healthy nonsmoking adults with low serum folate and supports the hypothesis that nitric oxide modulates homocysteine through an effect on folate catabolism. Folic Acid nitric oxide synthase 3 Homo sapiens