Pub. Date : 2003 May
PMID : 12684699
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Recently we found that macrophage colony-stimulating factor (M-CSF) inhibits 8-Br-cAMP-induced decidualization, differentiation to prolactin (PRL)-secreting cells, by suppressing viable decidualizing cells. | 8-Bromo Cyclic Adenosine Monophosphate | colony stimulating factor 1 | Homo sapiens |
2 | Recently we found that macrophage colony-stimulating factor (M-CSF) inhibits 8-Br-cAMP-induced decidualization, differentiation to prolactin (PRL)-secreting cells, by suppressing viable decidualizing cells. | 8-Bromo Cyclic Adenosine Monophosphate | colony stimulating factor 1 | Homo sapiens |
3 | A high concentration of M-CSF strongly suppressed the viable cell numbers and PRL secretion of stromal cells co-stimulated with 8-Br-cAMP and M-CSF, although G-CSF release from the co-stimulated stromal cells was not affected by M-CSF. | 8-Bromo Cyclic Adenosine Monophosphate | colony stimulating factor 1 | Homo sapiens |
4 | These results indicate that M-CSF enhances G-CSF secretion from 8-Br-cAMP-unstimulated human endometrial stromal cells but not from 8-Br-cAMP-stimulated stromal cells, thus suggesting that there exists a functional subpopulation of G-CSF-secreting stromal cells that are different from the predecidualized ESCs that differentiate into PRL-secreting ESCs under stimuli with 8-Br-cAMP. | 8-Bromo Cyclic Adenosine Monophosphate | colony stimulating factor 1 | Homo sapiens |