Pub. Date : 2003 Apr
PMID : 12679885
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The study was performed to describe the time course of serum cardiac troponin T (cTnT) elevations for the early detection of anthracycline cardiotoxicity. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |
| 2 | The study was performed to describe the time course of serum cardiac troponin T (cTnT) elevations for the early detection of anthracycline cardiotoxicity. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |
| 3 | cTnT was analyzed serially in 78 patients with hematological malignancies receiving 142 treatment cycles including various anthracyclines. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |
| 4 | Peak cTnT levels were observed on day +21.5 (median, range: day +6 to day +35) after initiation of anthracycline therapy. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |
| 5 | cTnT positivity lasted >or=3 days in 63% of cycles and began to occur after a median of two anthracycline doses. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |
| 6 | Serial measurement of serum cTnT reveals delayed subclinical myocardial damage even after minor anthracycline exposure, may identify patients at risk for subsequent myocardial dysfunction, and suggests prolonged damage to the cardiac myofibrillar system. | Anthracyclines | troponin T2, cardiac type | Homo sapiens |