Protein Name troponin T2, cardiac type
Organism Homo sapiens
Gene ID 7139
Gene Symbol

TNNT2

UniProt P45379 (TNNT2_HUMAN), A0A0A0MRJ5 (A0A0A0MRJ5_HUMAN), Q15607 (Q15607_HUMAN)
Relationships Total Number of functionally related compound(s) : 330
Total Number of Articles : 450
Description

troponin T2, cardiac type

Gene Summary

This gene encodes the cardiac isoform of troponin T. The encoded protein is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. [provided by RefSeq, May 2022]

synonyms
  • troponin T, cardiac muscle
  • cardiomyopathy, dilated 1D (autosomal dominant)
  • cardiomyopathy, hypertrophic 2
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Properties