Title : Total parenteral nutrition-stimulated activity of inducible nitric oxide synthase in rat pancreatic islets is suppressed by glucagon-like peptide-1.

Pub. Date : 2003 Jan

PMID : 12669271






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A dose-response study of GLP-1 with glucose-stimulated islets showed that GLP-1 could overcome and completely restore the impaired insulin release in TPN islets, bringing about a marked increase in islet cAMP accumulation concomitant with heavy suppression of both glucose-stimulated increase in islet cGMP content and the activities of constitutive NOS (cNOS) and iNOS. Glucose nitric oxide synthase 2 Rattus norvegicus