Title : Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.

Pub. Date : 2003 Apr 1

PMID : 12654483






1 Functional Relationships(s)
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1 Treatment with superoxide dismutase or Tiron to scavenge O2*-, or transfection with p22phox antisense oligonucleotides to inhibit O2*- production, attenuated 13-HPODE-induced cytotoxicity, but not that induced by 4-HNE. 4-hydroxy-2-nonenal cytochrome b-245 alpha chain Homo sapiens