Pub. Date : 2003 Mar 28
PMID : 12650967
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nitrous oxide-induced c-Fos expression in the rat brain. | Nitrous Oxide | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | N(2)O administration produced significant (P<0.05) dose-related increases of c-Fos expression in several forebrain regions, including the hypothalamic supraoptic and paraventricular nuclei, the thalamic paraventricular nucleus, the amygdala, and in retrosplenial cortex. | Nitrous Oxide | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | In the midbrain, N(2)O caused significant dose-related c-Fos expression in the Edinger-Westphal nucleus. | Nitrous Oxide | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | Finally, the pontine locus coeruleus, and two medullary regions, the nucleus of the solitary tract and ventrolateral medulla, also showed significant dose-related N(2)O-induced c-Fos expression. | Nitrous Oxide | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 5 | The overlapping pattern of c-Fos induced by ethanol and N(2)O suggests that these drugs may cause comparable central activity by acting on similar neuronal pathways. | Nitrous Oxide | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |