Title : Prodrugs to enhance central nervous system effects of the TRH-like peptide pGlu-Glu-Pro-NH2.

Pub. Date : 2003 Mar 24

PMID : 12643900






1 Functional Relationships(s)
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1 Potential prodrugs for the TRH-like tripeptide pGlu-Glu-Pro-NH(2) were synthesized either by esterifying the Glu side-chain of the parent peptide in solution with alcohols in the presence of resin-bound dicyclohexylcarbodiimide or by solid-phase peptide chemistry. Pyrrolidonecarboxylic Acid thyrotropin releasing hormone Mus musculus