Protein Name thyrotropin releasing hormone
Organism Mus musculus
Gene ID 22044
Gene Symbol

Trh

UniProt Q62361 (TRH_MOUSE)
Relationships Total Number of functionally related compound(s) : 249
Total Number of Articles : 195
Description

thyrotropin releasing hormone

Gene Summary

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The mouse proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Disruption of this gene results in hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, Apr 2013]

synonyms
  • thyrotropin releasing hormone
  • TSH-releasing factor
  • pro-thyrotropin-releasing hormone
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Properties