Title : Local tissue factor pathway inhibitor release in the human forearm.

Pub. Date : 2003 Mar

PMID : 12624625






3 Functional Relationships(s)
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1 Heparin caused a dose-dependent increase in plasma TFPI concentrations in both arms (ANOVA, p <0.0001). Heparin tissue factor pathway inhibitor Homo sapiens
2 Estimated net forearm TFPI release was 7 +/- 16, 29 +/- 20 and 138 +/- 72 ng/100 mL tissue/min during 10, 30 and 100 IU/min of heparin respectively (ANOVA, p <0.0001). Heparin tissue factor pathway inhibitor Homo sapiens
3 Compared to the systemic circulation, the forearm sensitivity to heparin induced TFPI release was 3.6-fold lower (166 +/- 67 ng/IU vs. 596 +/- 252 ng/IU: t-test, p = 0.004). Heparin tissue factor pathway inhibitor Homo sapiens