Title : Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.

Pub. Date : 2003 Mar 7

PMID : 12624268






2 Functional Relationships(s)
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1 Using Cyp1b1-/- mice, we identified the tyrosinase gene (Tyr) as a modifier of the drainage structure phenotype, with Tyr deficiency increasing the magnitude of dysgenesis. Tyrosine tyrosinase Mus musculus
2 The severe dysgenesis in eyes lacking both CYP1B1 and TYR was alleviated by administration of the tyrosinase product dihydroxyphenylalanine (l-dopa). Tyrosine tyrosinase Mus musculus