Pub. Date : 2003 Feb
PMID : 12623225
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regional differences in naloxone modulation of Delta(9)-THC induced Fos expression in rat brain. | Dronabinol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Results showed that naloxone inhibited THC-induced Fos immunoreactivity in several key brain regions including the ventral tegmental area, ventromedial and dorsomedial hypothalamus, central caudate-putamen and ventrolateral periaqueductal grey. | Dronabinol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Conversely, naloxone and THC had an additive effect on Fos immunoreactivity in the central nucleus of the amygdala, the bed nucleus of the stria terminalis (lateral division), the insular cortex, and the paraventricular nucleus of the thalamus. | Dronabinol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | The inhibitory effects of naloxone on THC-induced ventral tegmentum, hypothalamic and periaqueductal grey Fos expression point to these structures as key sites involved in cannabinoid-opioid interactions. | Dronabinol | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |