Title : Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster.

Pub. Date : 2003 Mar

PMID : 12618593






4 Functional Relationships(s)
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1 A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl. 2-aminofluorene N-acetyltransferase 2 Homo sapiens
2 A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl. 2-aminofluorene N-acetyltransferase 2 Homo sapiens
3 A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl. 2-aminofluorene N-acetyltransferase 2 Homo sapiens
4 NAT1 and NAT2 in liver and prostate catalysed -acetylation of the arylamines above and O-acetylation of N-hydroxy derivatives of 2-aminofluorene, 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 2-aminofluorene N-acetyltransferase 2 Homo sapiens