Title : Kynurenic acid enhances electroacupuncture analgesia in normal and carrageenan-injected rats.

Pub. Date : 2003 Mar 21

PMID : 12618353






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 injection of carrageenan, the number of Fos-like immunoreactive (Fos-LI) neurons was significantly increased in all layers of ipsilateral spinal cord at L(4)-L(5) with the higher density in laminae I-II and V-VI. Carrageenan Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 injection of carrageenan, the number of Fos-like immunoreactive (Fos-LI) neurons was significantly increased in all layers of ipsilateral spinal cord at L(4)-L(5) with the higher density in laminae I-II and V-VI. Carrageenan Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 Intrathecally pre-administered KYNA (10 nmol) significantly reduced the total number of carrageenan-induced Fos-LI neurons with more apparent reduction in laminae I-II and IV-V. Pre-coapplication of 10 nmol KYNA and EA of bilateral "Zu-San-Li" and "Kun-Lun" acupoints, the numbers of carrageenan-induced Fos-LI neurons in laminae I-II and V-VI further reduced. Carrageenan Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
4 Intrathecally pre-administered KYNA (10 nmol) significantly reduced the total number of carrageenan-induced Fos-LI neurons with more apparent reduction in laminae I-II and IV-V. Pre-coapplication of 10 nmol KYNA and EA of bilateral "Zu-San-Li" and "Kun-Lun" acupoints, the numbers of carrageenan-induced Fos-LI neurons in laminae I-II and V-VI further reduced. Carrageenan Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
5 The level of Fos expression in the spinal cord induced by carrageenan was significantly lower compared with that of i.t. Carrageenan Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus