Title : Suppression of tumor necrosis factor-alpha by beta2-adrenoceptor activation: role of mitogen-activated protein kinases in renal mesangial cells.

Pub. Date : 2003 Jan

PMID : 12608646






1 Functional Relationships(s)
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1 The selective MAPK/Erk-1 inhibitor, PD98059 (10(-5) M) and the specific p38 inhibitor SB203580 (10(-5) M) significantly decreased LPS-induced TNF-alpha production in the cells. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one tumor necrosis factor Rattus norvegicus