Title : Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.

Pub. Date : 2003 Mar

PMID : 12601032






2 Functional Relationships(s)
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1 RESULTS: EGF-stimulated peroxidase secretion in a concentration-dependent manner with a significant increase at 10(-7) M. EGF-stimulated secretion was inhibited by the EGF receptor (EGFR) inhibitor AG1478, but not by the phosphoinositide-3 kinase inhibitor LY292004 or the mitogen-activated kinase kinase (MEK) inhibitor U0126. U 0126 epidermal growth factor receptor Rattus norvegicus
2 RESULTS: EGF-stimulated peroxidase secretion in a concentration-dependent manner with a significant increase at 10(-7) M. EGF-stimulated secretion was inhibited by the EGF receptor (EGFR) inhibitor AG1478, but not by the phosphoinositide-3 kinase inhibitor LY292004 or the mitogen-activated kinase kinase (MEK) inhibitor U0126. U 0126 epidermal growth factor receptor Rattus norvegicus