Title : Effects of peripheral and central catechol-O-methyltransferase inhibition on striatal extracellular levels of dopamine: a microdialysis study in freely moving rats.

Pub. Date : 2003 Jan

PMID : 12573869






3 Functional Relationships(s)
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1 Effects of peripheral and central catechol-O-methyltransferase inhibition on striatal extracellular levels of dopamine: a microdialysis study in freely moving rats. Dopamine catechol-O-methyltransferase Rattus norvegicus
2 Tolcapone may also impair the extraneuronal catabolism of DA by inhibiting COMT activity in the brain. Dopamine catechol-O-methyltransferase Rattus norvegicus
3 ), both COMT inhibitors significantly increased striatal levels of L-DOPA and DA compared with saline. Dopamine catechol-O-methyltransferase Rattus norvegicus