Title : Trophic and steroidogenic effects of water deprivation on the adrenal gland of the adult female rat.

Pub. Date : 2003 Feb 28

PMID : 12573807






4 Functional Relationships(s)
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1 Water deprivation significantly increased plasma renin activity (PRA), plasma Angiotensin II (AII), vasopressin (AVP), epinephrine, aldosterone and corticosterone concentrations but did not modify the plasma adrenocorticotropin hormone (ACTH) level. Water angiotensinogen Rattus norvegicus
2 Water deprivation significantly increased plasma renin activity (PRA), plasma Angiotensin II (AII), vasopressin (AVP), epinephrine, aldosterone and corticosterone concentrations but did not modify the plasma adrenocorticotropin hormone (ACTH) level. Water angiotensinogen Rattus norvegicus
3 Water deprivation significantly increased the density of AII type 1 (AT(1)) receptors in the adrenal capsule but did not modify the density of AII type 2 (AT(2)) receptors in the adrenal capsule and core containing the zona fasciculata, the zona reticularis and the medulla. Water angiotensinogen Rattus norvegicus
4 In conclusion, these results suggest that AII seems to be the main factor involved in the stimulation of the growth and the secretion of aldosterone by the adrenal capsule containing the zona glomerulosa during water deprivation. Water angiotensinogen Rattus norvegicus