Pub. Date : 2003 Feb 28
PMID : 12573802
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of mRNA for PACAP and its receptors in intra- and extra-adrenal human pheochromocytomas and their relationship to catecholamine synthesis. | Catecholamines | adenylate cyclase activating polypeptide 1 | Homo sapiens |
| 2 | PURPOSE: Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the secretin/glucagons/vasoactive intestinal peptide family, induces the expression of catecholamine-synthesizing enzymes in adrenal medullary cells. | Catecholamines | adenylate cyclase activating polypeptide 1 | Homo sapiens |
| 3 | PURPOSE: Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the secretin/glucagons/vasoactive intestinal peptide family, induces the expression of catecholamine-synthesizing enzymes in adrenal medullary cells. | Catecholamines | adenylate cyclase activating polypeptide 1 | Homo sapiens |
| 4 | In addition, PACAP and its receptor have been detected in human pheochromocytoma tissues, though it is not yet known whether PACAP enhances the expression of genes encoding catecholamine-synthesizing enzymes. | Catecholamines | adenylate cyclase activating polypeptide 1 | Homo sapiens |
| 5 | CONCLUSION: Our findings support a possible role for PACAP in the regulation of expression of genes encoding catecholamine-synthesizing enzymes in intra-adrenal pheochromocytomas. | Catecholamines | adenylate cyclase activating polypeptide 1 | Homo sapiens |