Title : A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat.

Pub. Date : 2003 Feb

PMID : 12540628






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rats with 10 weeks of streptozotocin-induced diabetes and GHb levels of 16 +/- 2% (mean +/- SD) showed increased retinal levels of sorbitol and fructose, attenuation of GFAP immunostaining in astrocytes, appearance of prominent GFAP expression in Muller glial cells, and a fourfold increase in the number of apoptotic neurons when compared with nondiabetic rats. 4-hydroxybutyric acid glial fibrillary acidic protein Rattus norvegicus
2 Rats with 10 weeks of streptozotocin-induced diabetes and GHb levels of 16 +/- 2% (mean +/- SD) showed increased retinal levels of sorbitol and fructose, attenuation of GFAP immunostaining in astrocytes, appearance of prominent GFAP expression in Muller glial cells, and a fourfold increase in the number of apoptotic neurons when compared with nondiabetic rats. 4-hydroxybutyric acid glial fibrillary acidic protein Rattus norvegicus