Pub. Date : 2002 Oct
PMID : 12530470
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The involvement of P-glycoprotein in berberine absorption. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 2 | The aim of this study was to use the P-glycoprotein (P-glycoprotein) inhibitors cyclosporin A, verapamil and the monoclonal antibody C219 in in vivo and in vitro models of intestinal absorption to determine the role of P-glycoprotein in berberine absorption. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 3 | The aim of this study was to use the P-glycoprotein (P-glycoprotein) inhibitors cyclosporin A, verapamil and the monoclonal antibody C219 in in vivo and in vitro models of intestinal absorption to determine the role of P-glycoprotein in berberine absorption. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 4 | The aim of this study was to use the P-glycoprotein (P-glycoprotein) inhibitors cyclosporin A, verapamil and the monoclonal antibody C219 in in vivo and in vitro models of intestinal absorption to determine the role of P-glycoprotein in berberine absorption. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 5 | In the rat recirculating perfusion model, berberine absorption was improved 6-times by P-glycoprotein inhibitors. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 6 | P-glycoprotein appears to contribute to the poor intestinal absorption of berberine which suggests P-glycoprotein inhibitors could be of therapeutic value by improving its bioavailability. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 7 | P-glycoprotein appears to contribute to the poor intestinal absorption of berberine which suggests P-glycoprotein inhibitors could be of therapeutic value by improving its bioavailability. | Berberine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |