Title : STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA.

Pub. Date : 2003 Jan

PMID : 12529425






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 RhoA triggers tyrosine phosphorylation (Y696) of Stat5a via a JAK2-dependent mechanism and promotes DNA-binding activity of Stat5a. Tyrosine ras homolog family member A Homo sapiens
2 Thus, RhoA regulates Stat5a via tyrosine phosphorylation and via a yet to be determined novel down-modulating pathway that involves serine dephosphorylation. Tyrosine ras homolog family member A Homo sapiens