Title : Alpha 2 adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein: role of phosphatidylinositol 3-kinase and EGF receptor transactivation.

Pub. Date : 2003 Jan

PMID : 12522079






1 Functional Relationships(s)
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1 2 alpha(2) Adrenoceptor-mediated vasoconstriction and ERK2 activation in the porcine palmar lateral vein was inhibited in the presence of either the PI 3-kinase inhibitor LY294002, or the EGF receptor tyrosine kinase inhibitor AG1478 suggesting the involvement of both PI 3-kinase and EGF receptor transactivation. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one epidermal growth factor receptor Homo sapiens