Title : Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.

Pub. Date : 2003 Jan 2

PMID : 12502361






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MD studies on the binding mode of sparteine, quinidine, and quinine in CYP2D2 and CYP2D6 furthermore concurred well with experimentally determined IC(50) values and metabolic profiles. Quinine cytochrome P450, family 2, subfamily d, polypeptide 4 Rattus norvegicus