| Protein Name | cytochrome P450, family 2, subfamily d, polypeptide 4 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 171522 |
| Gene Symbol | Cyp2d4 |
| UniProt | Q64680 (CP2D4_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
134
Total Number of Articles : 105 |
Description |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
| Gene Summary |
Enables arachidonate monooxygenase activity and progesterone 21-hydroxylase activity. Involved in several processes, including carboxylic acid metabolic process; dopamine biosynthetic process; and response to toluene. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Biomarker of traumatic brain injury. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; extrapyramidal and movement disease; head and neck squamous cell carcinoma; leukemia (multiple); and major depressive disorder. Orthologous to several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)). [provided by Alliance of Genome Resources, Apr 2025] |
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| Properties | |