| Protein Name | cytochrome P450, family 2, subfamily d, polypeptide 4 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 171522 |
| Gene Symbol | Cyp2d4 |
| UniProt | Q64680 (CP2D4_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
134
Total Number of Articles : 105 |
Description |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
| Gene Summary |
Enables arachidonate monooxygenase activity and progesterone 21-hydroxylase activity. Involved in several processes, including carboxylic acid metabolic process; dopamine biosynthetic process; and response to toluene. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Biomarker of traumatic brain injury. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; extrapyramidal and movement disease; head and neck squamous cell carcinoma; leukemia (multiple); and major depressive disorder. Orthologous to several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |