Title : Insulin-like growth factor-I antagonizes the antiproliferative effects of cyclooxygenase-2 inhibitors on BxPC-3 pancreatic cancer cells.

Pub. Date : 2002 Dec 15

PMID : 12499282






1 Functional Relationships(s)
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1 Treatment of BxPC-3 cells with a higher dose (50 micro M) of celecoxib for 24 h resulted in the induction of apoptosis, as assayed by flow cytometry and poly(ADP-ribose) polymerase cleavage. Celecoxib poly(ADP-ribose) polymerase 1 Homo sapiens