Title : A pervasive mechanism for analgesia: activation of GIRK2 channels.

Pub. Date : 2003 Jan 7

PMID : 12493843






1 Functional Relationships(s)
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1 By using GIRK2-null mutant mice, we found marked reduction or complete elimination of the antinociceptive (hot plate test) effects of ethanol, oxotremorine, nicotine, baclofen, clonidine, and the cannabinoid receptor agonist WIN 55,212. Clonidine potassium inwardly-rectifying channel, subfamily J, member 6 Mus musculus