Title : Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.

Pub. Date : 2002 Nov 21

PMID : 12444545






1 Functional Relationships(s)
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1 When cells were synchronized in S phase with aphidicolin and then released, activation of Delta MEKK3:ER* resulted in the up-regulation of p21(CIP1) and a pronounced inhibition of cyclin A/CDK2 and cyclin B1/CDK1 kinase activity. Aphidicolin KRAS proto-oncogene, GTPase Rattus norvegicus