Pub. Date : 2002 Dec
PMID : 12438507
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine also elevated mRNA levels of GTP cyclohydrolase I (GTPCH), rate limiting in biosynthesis of TH"s essential cofactor tetrahydrobiopterin in both dopaminergic locations. | Nicotine | GTP cyclohydrolase 1 | Rattus norvegicus |
| 2 | Nicotine also elevated mRNA levels of GTP cyclohydrolase I (GTPCH), rate limiting in biosynthesis of TH"s essential cofactor tetrahydrobiopterin in both dopaminergic locations. | Nicotine | GTP cyclohydrolase 1 | Rattus norvegicus |
| 3 | Pretreatment with the alpha7 nAChR antagonist methyllycaconitine prevented the nicotine-induced rise in TH or GTPCH mRNA in VTA and SN. | Nicotine | GTP cyclohydrolase 1 | Rattus norvegicus |