Title : Insulin-like growth factor-binding protein-3 potentiates epidermal growth factor action in MCF-10A mammary epithelial cells. Involvement of p44/42 and p38 mitogen-activated protein kinases.

Pub. Date : 2003 Jan 31

PMID : 12433918






1 Functional Relationships(s)
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1 In IGFBP-3-primed cells, EGF-stimulated EGF receptor phosphorylation at Tyr-1068 was increased relative to unprimed cells, as was phosphorylation and activity of p44/42 and p38 MAP kinases, but not Akt/PKB. Tyrosine insulin like growth factor binding protein 3 Homo sapiens