Title : Isoprenoids influence expression of Ras and Ras-related proteins.

Pub. Date : 2002 Nov 19

PMID : 12427032






2 Functional Relationships(s)
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Protein Name
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1 Studies utilizing specific isoprenoid pyrophosphates in mevalonate-depleted cells reveal that farnesyl pyrophosphate (FPP) restores Ras processing and prevents RhoB upregulation while geranylgeranyl pyrophosphate (GGPP) restores Rap1a processing and prevents RhoA and RhoB upregulation. farnesyl pyrophosphate RAP1A, member of RAS oncogene family Homo sapiens
2 Studies utilizing specific isoprenoid pyrophosphates in mevalonate-depleted cells reveal that farnesyl pyrophosphate (FPP) restores Ras processing and prevents RhoB upregulation while geranylgeranyl pyrophosphate (GGPP) restores Rap1a processing and prevents RhoA and RhoB upregulation. farnesyl pyrophosphate RAP1A, member of RAS oncogene family Homo sapiens