Title : The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3.

Pub. Date : 2003 Feb 15

PMID : 12406902






1 Functional Relationships(s)
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1 Our results show that SU5614 is a PTK inhibitor of FLT3 and has antiproliferative and proapoptotic activity in AML-derived cell lines that endogenously express an activated FLT3 receptor. SU 5614 fms related receptor tyrosine kinase 3 Homo sapiens