Title : GM-CSF, via PU.1, regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma -mediated molecular connection between innate and adaptive immunity in the lung.

Pub. Date : 2002 Dec 1

PMID : 12393686






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Opsonophagocytosis by GM(-/-) AMs was severely impaired and was restored by pulmonary GM-CSF expression in vivo or by PU.1 expression in vitro. gm colony stimulating factor 2 (granulocyte-macrophage) Mus musculus
2 IL-18 expression by GM(-/-) AMs was severely impaired and was restored by pulmonary GM-CSF expression in vivo or by PU.1 expression in vitro. gm colony stimulating factor 2 (granulocyte-macrophage) Mus musculus