Protein Name colony stimulating factor 2 (granulocyte-macrophage)
Organism Mus musculus
Gene ID 12981
Gene Symbol

Csf2

UniProt P01587 (CSF2_MOUSE), Q5SX78 (Q5SX78_MOUSE)
Relationships Total Number of functionally related compound(s) : 715
Total Number of Articles : 950
Description

colony stimulating factor 2 (granulocyte-macrophage)

Gene Summary

Enables cytokine activity. Acts upstream of or within several processes, including embryonic placenta development; myeloid leukocyte differentiation; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including genitourinary system; hemolymphoid system; labyrinthine zone; liver; and lung. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • granulocyte-macrophage colony-stimulating factor
  • colony-stimulating factor
  • granulocyte-macrophage colony stimulating factor 2
Click to show/hide the synonyms
Properties