Title : Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.

Pub. Date : 2003 Mar 1

PMID : 12393499






3 Functional Relationships(s)
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1 Furthermore, analysis of different mitogen-activated protein (MAP) kinase signaling pathways revealed that p38 signaling was activated following apicidin treatment of cells and that inhibition of this pathway abolished the HbF-inducing effect of apicidin. apicidin mitogen-activated protein kinase 14 Homo sapiens
2 Furthermore, analysis of different mitogen-activated protein (MAP) kinase signaling pathways revealed that p38 signaling was activated following apicidin treatment of cells and that inhibition of this pathway abolished the HbF-inducing effect of apicidin. apicidin mitogen-activated protein kinase 14 Homo sapiens
3 Additionally, activation of the Agamma-globin promoter by apicidin could be inhibited by p38 inhibitor SB203580. apicidin mitogen-activated protein kinase 14 Homo sapiens